Assuming you are using Unreal (since most people do). Add this line to your config file (unrealircd.conf).
include "aliases/anope.conf";
Then save and /rehash. If you have services-server correct then the /ns, /cs .. etc .. aliases will work.
All this top secret Uber knowledge is courtesy of the Official Unreal Documentation found at:
http://www.vulnscan.org/UnrealIrcd/unreal32docs.htmlIf you use another ircd, then it should have some top secret documentation as well found on the ircd's website or inconveniently located in the install directory obscurely named "doc" or "docs".